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From:bounce-otcjournal-3119263@lyris.otcjournal.com
To:h..lewis@enron.com
Subject:The BioTech Revolution- Profits Imminent in the 1st Decade of this
Cc:
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Date:Sat, 19 Jan 2002 12:39:35 -0800 (PST)

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[IMAGE] January 19, 2002 [IMAGE] [IMAGE] Volume V, Issue 6 [IMAGE] =
Email : info@otcjournal.com URL : http://www.otcjournal.com To OTC Jou=
rnal Members: [IMAGE] Special Note [IMAGE] Many of you may have notice=
d Wednesday's edition of the OTC Journal did not arrive in your inbox until=
Thursday or Friday. There seems to be delivery challenges on the Internet =
which may be related to the recent demise of @Home. You can always visit ht=
tp://listserv.otcjournal.com to find our most current edition before it ar=
rives in your mail. Please save this web address in your favorites on your =
browser. [IMAGE] The BioTech Revolution- A Leading Group For the First=
Decade of the 21st Century [IMAGE] Vast fortunes were accumulated in th=
e 80's and 90's as the computer evolved into an integral part of our daily =
lives. Companies like Microsoft, Cisco, Oracle, Intel, Sun Microsystems, an=
d Dell Computer yielded massive profits for shareholders during the twenty =
five year meteoric growth phase of this industry. The BioTech industry is=
poised to provide those same kind of returns in the first decade of the 21=
st Century. The fruits of innovative research will propel more new drugs to=
market than ever before. The paradigm has shifted from technology/internet=
companies to BioTech. Serving as evidence of this paradigm shift is the =
recent "rebalancing" of the NASDAQ 100. Thirteen companies were booted off;=
all of them technology. Of the thirteen newly added; eight of them are Bio=
Tech. During the 10 year period between 1976 and 1985 the FDA approved ju=
st 198 new drugs. Last year alone, the number of new drug approvals skyrock=
eted to 160. That figure is expected to climb even higher in 2002. At prese=
nt, an astonishing 643 new pharmaceuticals are nearing the final stages of =
the FDA's testing and approval process according to a recent report prepare=
d for the US Government. Enormous returns are likely for investors in the r=
ight companies as some of these 643 new therapies come to market. [IMAG=
E] Factors Fueling the BioTech Revolution [IMAGE] [IMAGE] The chart of th=
e biotech index reveals a 53% climb to the upside from the September low to=
the early December high. Stocks have given back ground recently as company=
guidance for the immediate future is sobering. This "reality" correction o=
f the last three weeks has yielded a 50% retrenchment in the biotech index,=
suggesting entry levels are becoming attractive again. The BioTech revol=
ution is being fueled by many factors. Expedited FDA Approval procedures we=
re implemented during the Clinton Administration, reducing the average clin=
ical testing period from 15 years down to 5 years. In addition, the recen=
t breakthroughs in Human Genome Mapping have provided bio-scientists with r=
evolutionary new tools to aid in identifying the underlying causes of disea=
se and help accelerate the pace of the development of potential cures. Comp=
anies like Human Genome Sciences (NASDAQ: HGSI) are providing bio-scientist=
s with exciting new tools to help speed the development of revolutionary tr=
eatments. While it is estimated the FDA approval process requires an inve=
stment north of $150 million, the return on investment associated with a su=
ccessful new drug introduction is staggering. 40% to 50% of new drugs makin=
g it to Stage III clinical trials never get approved, but successful approv=
als can generate billions in profits for drug companies. In other parts o=
f the world, barriers to entry are more relaxed for new drugs, causing incr=
eased competition, lower margins, and lower profits. Patent protection and =
stringent FDA requirements still keep the US pharmaceutical market position=
ed as the most coveted in the world. [IMAGE] Potential Major Breakthrou=
ghs [IMAGE] The following is a list of potential major breakthroughs for 2=
002: ViroPharma (NASDAQ: VPHM): The Common Cold. ViroPharma is developing=
Picovir, purported to be the magic cure for the common cold. The company s=
pecializes in novel therapeutics for the treatment of diseases caused by RN=
A viruses. Such viruses are responsible for a host of common disorders, inc=
luding certain types of meningitis, hepatitis, and the common cold. Many an=
alysts feel an approval could be coming late this year for Picovir. Maxim P=
harmaceuticals (NASDAQ: MAXM): Cancer Therapy. The Company's lead drug cand=
idate, Ceplene?, is currently being tested in Phase 3 cancer clinical trial=
s in 12 countries for malignant melanoma and acute myelogenous leukemia, an=
d in Phase 2 trials for the treatment of hepatitis C and renal cell carcino=
ma. Medarex (NASDAQ: MEDX): Arthritis. Phase III trials were recently start=
ed on MDX-CD4, a treatment for rheumatoid arthritis. MDX-010 is currently u=
ndergoing several multi center Phase Phase I/II trials in prostate cancer, =
melanoma and other malignancies. Axcan Pharma (NASDAQ: AXCA): Ulcers and Ot=
her Stomach Problems. Axcan is a leading specialty pharmaceutical company w=
ithin the field of gastroenterology in North America and Europe. This compa=
ny posted fiscal year revenues of $104.5 million dollars and earnings of $1=
1.5 million. Helicide, Axcan's patented, oral, single capsule, triple thera=
py treatment for H. Pylori infection (the leading cause of peptic ulcers an=
d a potential cause of gastric cancer) should be FDA approved later this ye=
ar. DUSA Pharmaceuticals (NASDAQ: DUSA): Cancer Detection. The company's ma=
in product Levulan
PDT/PD is a platform used for the detection and treatment of a variety of =
superficial conditions, such as early cancers, pre cancers and skin conditi=
ons. Levulan apparently has wider applications and may add to the bottom li=
ne in the not too distant future. DUSA initiated three Phase I/II Levulan P=
DT clinical trials. As mentioned earlier, 160 new drugs were approved by t=
he FDA last year. There are currently 643 new drugs with a realistic chance=
of success in the FDA pipeline. Companies will make staggering profits as =
many of these new therapies come to market, and investors in the right stoc=
ks will enjoy the ride. [IMAGE] Upcoming OTC Journal Profile [IMAGE] T=
he OTC Journal plans to focus a great deal of energy in the BioTech sector.=
This sector is high risk/high reward, and therefore fits with our theme. B=
ioTech could replace computer technology as the boom group of the next deca=
de, and we intend to participate with ideas for our members. In the near =
future the OTC Journal will release a profile on an exciting medical device=
manufacturer that is benefiting from new drug therapies. The stock will op=
en for trading on the American Stock Exchange. It is going public through a=
n RTO, as described in our last edition . Therefore, all investors will be =
on equal ground once the stock begins trading. There will be no IPO stock a=
llocated to preferred institutional investors at a substantial discount pri=
or to the opening of trading. The company is already generating significa=
nt revenues through one FDA approval, and another is imminent. Currently, t=
here are nearly thirty new drugs in the FDA pipeline that could potentially=
benefit this company. The company does not invest vast sums of capital i=
n the FDA approval process. Their pharmaceutical partners do it for them, w=
hich mitigates a great deal of the risk associated with this type of invest=
ment. Early stage investors include some of the most high profile names o=
n Wall Street, seasoned industry experts, and pharmaceutical manufacturers.=
Sound interesting? Stand by for Tuesday's edition for more details. The =
opportunity may come as soon as next Friday, January 25th, and you need to =
be ready to act if you want to be a ground floor participant. Charts Prov=
ided Courtesy Of TradePortal.com The OTC Journal is a proud partner of t=
he SwingWire.com Online Investment Community . A next generation Online Ana=
lyst Exchange providing Members the ability to search, review, track and mo=
nitor some of the Internet's best Online CAs (CyberAnalysts). Members have =
the opportunity to potentially achieve higher returns by viewing top perfor=
ming portfolios and receiving real-time alerts from favorite CAs. SwingW=
ire.com also has a lucrative incentive model for experienced investors and=
traders who consistently outperform the market. Share market ideas with ot=
her like-minded investors, establish a proven track record, provide insight=
ful commentary, attract followers and ultimately become one of the Internet=
's highest paid and most sought after CyberAnalysts! Click here to recei=
ve your FREE 30-Day Trial Membership with no further obligation. Sign Up To=
day! Disclaimer The OTCjournal.com Newsletter is an independent el=
ectronic publication committed to providing our readers with factual inform=
ation on selected publicly traded companies. All companies are chosen on t=
he basis of certain financial analysis and other pertinent criteria with a =
view toward maximizing the upside potential for investors while minimizing=
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ublication accepts compensation from certain of the companies which it feat=
ures. Likewise, this newsletter is owned by MarketByte, LLC. To the degre=
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